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CV of Team leader Chimie Médicinale / Project manager / Team leader / Excellence manager , looking for a job of Décidé à orienter ma carrière vers la gestion de l’innovation, l’accompagnement stratégique et l’aid / posts.enligne-ch.com

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Senior scientist in chemistry looking for new challenges in project management and continuous excellence in R&D

CV Code: 5a5768cc2a3cba07
Date of last connection: 2018-02-22

Mr. Lo... T...
....
06410 Biot
France




Current situation:
Current industry: Pharmaceutique
Size of the company: More than 1,000 employees
Current position: Team leader Chimie Médicinale
Number of years spent at this position: 3-5 years
Number of persons you managed: 6-10 persons
Annual salary: 54000.00 EUR
Total working experience: 6-10 years
Availability: 3-months notice
Job sought:
Positions: Project manager / Team leader / Excellence manager, ,
Industry: Chimie-biochimie, ,

Desired type of contract: open-ended contract, fixed term contract
Desired working time: Full-time
Minimum annual salary desired: 0.00 / 0.00 EUR
Education:
Highest educational level completed: number of years studied and completed with a diploma after highschool : +8
Last diploma : Ph.D. IN CHEMISTRY
Current educational level : +8
Other training courses :


Geographical mobility:
Country : United States, Switzerland

Known Tools / Software/ Methods
Pharma  Wide range of chemistry: heterocyclic, nucleosides, peptides, polypropionates, hydrogels and hyaluronic acid.  Various synthetic strategies: transition metal catalyzed coupling, asymmetric catalysis, stereoselective transformations, cross coupling metathesis reactions.  Common techniques of purification and analysis of organic compounds by NMR, GC, HPLC, Mass Spectrometry, IR, DSC, X-RPD.  Drug design and medicinal chemistry (kinase inhibitors, proteases, G protein–coupled receptors).  Knowledge of scale-up and process development in fine chemistry (Scientific Update training). Technology  Flow chemistry (Vapourtec), high-throughput screening with iChemExplorer and microwave assisted organic synthesis. Computing  Scifinder, Reaxys, Agilent’s Electronic Lab Notebook, Dotmatics Software Suite, Chemdraw, Isisdraw, MestReNova, Word, Excel, Outlook, PowerPoint, SharePoint, Zotero, EndNote. Teaching  Teaching assistant in Organic Chemistry (UCBL1 and CPE), practical work and tutorial (290h).  Supervised students (2Ph.D. and 10MSc).

HGV, LGV, special vehicles licences
B

Languages
English : Fluent
Spanish : Fluent
French : Native



Resume:

Mr. Lo... T
06410 Biot
France


PROFIL








Six years’ experience as synthesis team manager in research
chemistry. Dynamic, thorough, team-oriented, capable to lead/motivate teams through
innovative problem-solving and a strong ability for project delivery.








HIGHLIGHTS










§ Adaptability/Open-minded

§ Proactive

§ Multi-tasking



§ Project management

§ Team coordination

§ Result orientation



§ Organization skill

§ Written/oral communication

§ Process improvement










PROFESSIONAL EXPERIENCE










2014 – Present



SYNTHESIS TEAM LEADER -Nestlé
Skin Health, Sophia Antipolis, France.


Lead, organize and participate to synthesis work as deputy head
of Research Synthesis










Key achievements:

§ Drove a team of chemists internally (up to 10) to deliver
complex and innovative synthetic routes leading to the nomination of kinase
inhibitor candidates.



§ Managed and coordinated synthesis within research chemistry by
regular meeting with drug designers.



§ Led outsourced research projects and organized regular meeting
with contract research organizations.



§ Contributed to the overall group synthesis strategy, trained
chemists and set yearly global objective with a net result of 50% increase in
key performance indicators (over three years).



§ Lean Six Sigma certified and participated in a green belt
project to drive project delivery.



§ Realized the laboratory refurbishment to improve safety, productivity
& ergonomics (100k€ budget) as health and safety manager of chemistry (~30 scientists).



§ Involved in 5 publications and 3 external presentations
surrounding breakthrough synthetic strategies.





2012 – 2014



LEAD SYNTHETIC SCIENTIST- Galderma
R&D, Sophia Antipolis, France.


Synthesis in medicinal chemistry, project management and
scientific advisor










Key achievements:

§ Co-led the synthesis internally & externally and managed
sourcing, collaborations and fee for service requests to deliver three drug
candidates.



§ Launched & developed a new flow chemistry platform to support
high-throughput drug delivery through scale-up of intermediates and transformation
of hyaluronic acid derivatives.



§ Contributed to internal medchem/devchem problem-solving group to
facilitate project transfer.



§ Trained internal chemists on strategic choices and structural
analysis to facilitate project delivery.





2010 – 2012



POSTDOCTORAL RESEARCH -
Institut des Sciences Moléculaires (iSm2), Marseille,
France.


Total synthesis of callystatin A (Supervisor: Pr. Cyril Bressy and Pr. Jean-Marc Pons)









Key achievements:

§ Realized a three fragments (4, 15 and 13 steps)
convergent synthesis enabled by enzymatic
enantioselective desymmetrization of meso diols, diastereoselective crotylstannylation, transition metal catalyzed reactions (Pd, Rh) and cross coupling
metathesis
.



§ Animated/participated
to weekly scientific literature seminar and monthly work presentation.







2005 – 2006



PROCESS CHEMIST RESEARCHER -
Rhodia Inc. PPD, Charleston (South
Carolina), USA.


Organophosphorus performance compound synthesis, development
and production










Key achievements:

§
Studied and improved a process for scale-up and participated to
pilot production.




§ Monthly
presented progress report to team leader and customers.





Aug. 2004



ANALYTICAL CHEMIST INTERN -
Labo-Services, Givors (69), France.


Organic waste analyses by gas chromatography, Titration and X
ray-fluorescence











EDUCATION










2007 – 2010



Ph.D.
IN TOTAL SYNTHESIS OF BISTRAMIDE A (GRANTED BY THE MINISTRY OF RESEARCH)


Supervisor: Dr. David Gueyrard and Pr. Peter G. Goekjian

Laboratoire de Chimie
Organique II–Glycochimie, Lyon, France.










Key achievements:

§
Developed and optimized a new
enol ether formation based on Julia-Kocienski olefination of a lactone.
Methodology was applied to total synthesis of Bistramide A (5 publications).




§ Regular scientific communications and mentoring
of students (3MSc + 1Ph.D).





2006 – 2007



MASTERS DEGREE IN “ORGANIC CHEMISTRY AND BIOACTIVE MOLECULE
SYNTHESIS”


Université Claude Bernard Lyon I, Lyon,
France (Masters with
honors).






2001 – 2007



DIPLOMA IN
CHEMISTRY AND PROCESS ENGINEERING (HE 5)


CPE Lyon – Lyon School of Chemistry, Physics and Electronics,
France.


2003-2007: Complete education in organic and
molecular chemistry, catalysis, analytical sciences, biology and process
engineering.









2001-2003: Two years of full-time higher education in
Mathematics, Science and General Studies, in preparation for selective
admission to CPE Lyon.










SCIENTIFIC
SKILLS











Pharma



§ Wide range of chemistry: heterocyclic, nucleosides, peptides,
polypropionates, hydrogels and hyaluronic acid.



§ Various synthetic strategies: transition metal catalyzed
coupling, asymmetric catalysis, stereoselective transformations, cross
coupling metathesis reactions.



§ Common techniques of purification and analysis of organic
compounds by NMR, GC, HPLC, Mass Spectrometry, IR, DSC, X-RPD.



§ Drug
design and medicinal chemistry (kinase inhibitors, proteases, G protein–coupled
receptors).



§ Knowledge
of scale-up and process development in fine chemistry (Scientific Update
training).





Technology



§ Flow chemistry (Vapourtec), high-throughput screening with
iChemExplorer and microwave assisted organic synthesis.





Computing



§ Scifinder, Reaxys, Agilent’s Electronic Lab Notebook, Dotmatics
Software Suite, Chemdraw, Isisdraw, MestReNova, Word, Excel, Outlook,
PowerPoint, SharePoint, Zotero, EndNote.





Teaching





§ Teaching assistant in Organic Chemistry (UCBL1 and CPE), practical
work and tutorial (290h).



§ Supervised
students (2Ph.D. and 10
MSc).










LANGUAGES










French



Native.





English



Fluent (Cambridge Certificate: Grade A).





Spanish



Written and oral, for professional purposes.










ACTIVITIES














Basketball,
scuba diving, squash, clarinet, cinema, gadgets & new technologies.










AWARDS










Oral com.



§
Grant from Lapervenchelif
association awarded by Dr. Robert H. Dodd, (Institut de Chimie des Substances Naturelles, Paris) for poster
presentation at the European
Symposium on Organic Chemistry, Prague,
July 2009, Czech Republic.





§ Best communication award at SECO 47, 47ème Semaine d'Etude de Chimie Organique, Seignosse,
May 2010, France.



§ Invited speaker at 3èmes
et 5èmes Journées Méditerranéennes des Jeunes Chercheurs,
Montpellier, Octobre 20015 et 2017, France.




Cover letter

Mr. Lo... T
06410 Biot
France

Senior scientist in chemistry looking for new challenges in project management and continuous excellence in R&D


Six years’ experience as synthesis team manager in research chemistry. Dynamic, thorough, team-oriented, capable to lead/motivate teams through innovative problem-solving and a strong ability for project delivery.Speciality :-R&D, pharmaceutical industry, Medicinal chemistry, Synthetic strategy, Total synthesis of Natural Compounds, Retrosynthesis.-Analytical techniques : HPLC, GC, NMR (1D & 2D), LCMS, IR, UV-Scientific project management, Outsourcing management, Scientific coaching, Lean processes for R&D.-Experience in scale-up and optimization of processes for piloting campaign.

Mr. Lo... T...


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